Jack Boone began his coaching career at East Carolina in 1948 as head coach of the East Carolina baseball team and as an assistant football coach.
Boone's baseball teams compiled a 38-23-2 record in three seasons for a .623 winning percentage. In 1952, he took over as the head football coach and held that position until 1961. He compiled a record of 49-45-5 and led the Pirates to their first bowl game appearance in 1952 and again in 1953.
In 1953, Boone was named as the Coach-of-the-Year in the North State Conference after his team finished 8-2. Even after 1961, Boone continued his association with ECU and worked as an assistant coach under former player Ed Emory in the 1980s.
Boone has been credited with "laying the groundwork for what followed in the years to come at ECU."